منابع مشابه
A Model of Authors’ Generic Competence of EAP Research Articles: A Qualitative Meta-Synthesis Approach
Genre analysis as an area of great concern in recent decades, involves the observation of linguistic features used by a determined discourse community. The research article (RA) is one of the most widely researched genres in academic writing which is realized through some rhetorical moves and discursive steps to achieve a communicative purpose. This study aimed at proposing a model of generic p...
متن کاملAntiepileptic drugs: the drawbacks of generic substitution.
The need to curb the rising costs of health care has led policy-makers in many countries to consider widespread generic substitution of brand-name drugs as an eff ective means to cut costs. For example, on January 5, 2010, the NHS in England began a 3-month consultation to seek views on plans to automatically substitute branded drugs with generic versions in primary care. However, doctors, pati...
متن کاملGeneric substitution: issues for problematic drugs.
The methodology and criteria for bioequivalence testing have been firmly established by the Food and Drug Administration (FDA). For certain drugs with a narrow therapeutic index (e.g., digoxin, levothyroxine, warfarin), generic substitution may not be advisable or even allowable, depending on the substitution laws of individual states. Digoxin and levothyroxine tablets are examples of drugs for...
متن کاملGeneric substitution in the treatment of epilepsy
Results: Fifty patients, well-controlled on a brand AED, subsequently experienced a breakthrough seizure or increased seizure frequency after switching to a generic without other provoking factors. AEDs included phenytoin (15 cases), valproic acid (14), carbamazepine (7), gabapentin (8), and zonisamide (8). Two patients were on a combination of two AEDs, both of which were switched to generics....
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2011
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2010.03878.x